SCHEMBL17211587

SCHEMBL17211587

CC(=O)Nc1cccc(/N=N\c2ccc(NC(C)=O)cc2O)c1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.53
RAB9A P51151 3/20 0.53
NPC1 O15118 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
THRB P10828 1/20 0.52
ALDH1A1 P00352 3/20 0.51
CYP1A2 P05177 1/20 0.51
AMY1A P0DUB6 3/20 0.51
LMNA P02545 1/20 0.49
HPGD P15428 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
HSD17B10 Q99714 1/20 0.47
PKM P14618 1/20 0.47
POLB P06746 2/20 0.44
TP53 P04637 1/20 0.44
NR4A1 P22736 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15883590 0.87 THRB (0.68) MAPTRAB9ANPC1SMN1; SMN2THRB
SCHEMBL10494616 0.82 MAPT (0.72) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL10494613 0.82 MAPT (0.72) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL3276097 0.77 PKM (0.56) MAPTRAB9ANPC1SMN1; SMN2THRB
SCHEMBL12130854 0.75 ALDH1A1 (0.59) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL12927928 0.74 MAPT (0.56) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL30318924 0.74 MAPT (0.56) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL11804711 0.73 ALDH1A1 (0.58) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL13190198 0.73 ALDH1A1 (0.58) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL2921891 0.73 ALDH1A1 (0.57) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9981227-B2 Composite polyamide membrane having azo content and high acid content DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-29 US disclosed
US-9616392-B2 Composite polyamide membrane having high acid content and low azo content DOW GLOBAL TECHNOLOGIES LLC (US) 2017-04-11 US disclosed
US-9555378-B2 Composite polyamide membrane having preferred azo content DOW GLOBAL TECHNOLOGIES LLC (US) 2017-01-31 US disclosed
US-20160317980-A1 COMPOSITE POLYAMIDE MEMBRANE HAVING HIGH ACID CONTENT AND LOW AZO CONTENT THE DOW CHEMICAL COMPANY 2016-11-03 US disclosed
US-20160310909-A1 COMPOSITE POLYAMIDE MEMBRANE HAVING AZO CONTENT AND HIGH ACID CONTENT THE DOW CHEMICAL COMPANY 2016-10-27 US disclosed
US-20160303520-A1 COMPOSITE POLYAMIDE MEMBRANE HAVING PREFERRED AZO CONTENT THE DOW CHEMICAL COMPANY 2016-10-20 US disclosed
US-20150314243-A1 COMPOSITE POLYAMIDE MEMBRANE INCLUDING TRI-HYDROCARBYL PHOSPHATE DOW CHEMICAL JAPAN LIMITED (JP) 2015-11-05 US disclosed
US-20150306548-A1 COMPOSITE POLYAMIDE MEMBRANE MADE VIA INTERFACIAL POLYMERIZATION USING A BLEND OF NON-POLAR SOLVENTS DOW GLOBAL TECHNOLOGIES LLC 2015-10-29 US disclosed