Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MB | P02144 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12589736 | 0.82 | ALDH1A1 (0.54) | PKMSMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL15883590 | 0.80 | THRB (0.68) | PKMSMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL90480 | 0.79 | ALDH1A1 (0.39) | PKMSMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL3192352 | 0.79 | PKM (0.65) | PKMSMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL10288515 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2POLBMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15360395 | 0.78 | ALDH1A1 (0.38) | PKMSMN1; SMN2POLBMAPTALDH1A1 | |
| SCHEMBL13699547 | 0.77 | MEN1 (0.48) | SMN1; SMN2POLBMAPTMEN1KMT2A | |
| SCHEMBL17211587 | 0.77 | MAPT (0.53) | PKMSMN1; SMN2POLBMAPTALDH1A1 | |
| SCHEMBL4958020 | 0.76 | MAPT (0.69) | PKMSMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL8537529 | 0.76 | ALDH1A1 (0.62) | PKMSMN1; SMN2POLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928160-A | A kind of preparation method of cresol-purple perchlorate | 大连九信精细化工有限公司 | 2017-07-07 | — | — | CN | claimed |
| US-20120015962-A1 | PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | ARORA NIDHI (US) | 2012-01-19 | — | — | US | disclosed |
| US-7695930-B2 | Method for the detection, identification and/or quantification of microoganisms with peptidase activity using phenoxazinone derivatives as enzyme substrates | BIOMERIEUX (FR) | 2010-04-13 | — | — | US | disclosed |
| US-20080286820-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2008-11-20 | — | — | US | disclosed |
| US-7420054-B2 | Phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2008-09-02 | — | — | US | disclosed |
| EP-1625117-B1 | NOVEL PHENOXAZINONE DERIVATIVES AS ENZYME SUBSTRATES AND USE THEREOF AS INDICTOR IN THE DETECTION OF MICROORGANISMS WITH PEPTIDASE ACTIVITY | BIOMERIEUX SA (FR) | 2008-01-09 | — | — | EP | disclosed |
| US-20060121551-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2006-06-08 | — | — | US | disclosed |
| EP-1625117-A1 | NOVEL PHENOXAZINONE DERIVATIVES AS ENZYME SUBSTRATES AND USE THEREOF AS INDICTOR IN THE DETECTION OF MICROORGANISMS WITH PEPTIDASE ACTIVITY | BIOMERIEUX (FR) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101536-A1 | NOVEL PHENOXAZINONE DERIVATIVES AS ENZYME SUBSTRATES AND USE THEREOF AS INDICTOR IN THE DETECTION OF MICROORGANISMS WITH PEPTIDASE ACTIVITY | BIOMERIEUX (FR) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060121551-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | PEPD, CTRL, PM20D2 | PKM 754/4885SMN1; SMN2 4814/4885POLB 1592/4885 |
| US-20120015962-A1 | PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | IRAK4, IRAK1, IRAK2 | PKM 570/4885SMN1; SMN2 1363/4885POLB 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.