Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17211756 | 0.90 | L3MBTL1 (0.54) | L3MBTL1KDM4ECTSDHCAR2KDM6B | |
| SCHEMBL17213442 | 0.85 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9APAX8KDM4E | |
| SCHEMBL19377597 | 0.75 | KDM4E (0.42) | L3MBTL1KDM4EHCAR2KDM6BKDM4A | |
| SCHEMBL29626163 | 0.75 | KDM4E (0.42) | L3MBTL1KDM4EHCAR2KDM6BKDM4A | |
| SCHEMBL17211672 | 0.74 | ALDH1A1 (0.52) | L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL19207113 | 0.65 | JMJD6 (0.44) | L3MBTL1NPC1RAB9APAX8KDM4E | |
| SCHEMBL30672122 | 0.65 | GRM5 (0.40) | NPC1KDM4EKDM6BKDM4AKDM5C | |
| Dipyridyl SCHEMBL4881410 | 0.65 | KDM4E (0.67) | L3MBTL1NPC1RAB9AKDM4EBRD4 | |
| Dipyridyl SCHEMBL9641711 | 0.65 | KDM4E (0.67) | L3MBTL1NPC1RAB9AKDM4EBRD4 | |
| Dipyridyl SCHEMBL11231947 | 0.65 | KDM4E (0.67) | L3MBTL1NPC1RAB9AKDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340532-B2 | Methods and compositions for inhibiting CNKSR1 | PHUSIS THERAPEUTICS, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20150307482-A1 | METHODS AND COMPOSITIONS FOR INHIBITING CNKSR1 | PHUSIS THERAPEUTICS, INC. (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307482-A1 | METHODS AND COMPOSITIONS FOR INHIBITING CNKSR1 | CNKSR1, CAMKK1, CAMKK2 | L3MBTL1 1932/4885NPC1 1500/4885RAB9A 3396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.