Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL612615 | 0.76 | PDE4B (0.37) | PIK3CDPDE4BGPR119HSD11B1MMP9 | |
| SCHEMBL609220 | 0.76 | PDE4B (0.37) | PIK3CDPDE4BGPR119HSD11B1 | |
| SCHEMBL1721052 | 0.75 | GPR119 (0.44) | GPR119FAAHMMP9 | |
| SCHEMBL1721381 | 0.74 | GPR119 (0.43) | PDE4BGPR119FAAH | |
| SCHEMBL1721777 | 0.72 | CHRNB2 (0.38) | PDE4BGPR119FAAH | |
| SCHEMBL15835945 | 0.72 | GPR119 (0.46) | PDE4BGPR119FAAH | |
| SCHEMBL610301 | 0.70 | GPR119 (0.38) | PDE4BGPR119FAAHMMP9 | |
| SCHEMBL457657 | 0.69 | GPR119 (0.38) | GPR119HSD11B1FAAHMMP9 | |
| SCHEMBL28870297 | 0.68 | GPR119 (0.50) | GPR119FAAHMMP2MMP9 | |
| SCHEMBL608827 | 0.68 | PDE4B (0.40) | PIK3CDPDE4BGPR119HSD11B1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406256-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103335-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |