Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.62 |
| ▸ | CTSL | P07711 | 4/20 | 0.62 |
| ▸ | CTSS | P25774 | 4/20 | 0.62 |
| ▸ | CTSB | P07858 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
| ▸ | PLAT | P00750 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17219933 | 0.83 | CTSL (0.62) | CTSKCTSLCTSSCTSBKMT2A | |
| SCHEMBL796672 | 0.82 | CTSK (0.61) | CTSKRAB9AMEN1KMT2AKDM4E | |
| SCHEMBL17220462 | 0.78 | MAPK1 (0.60) | CTSKCTSLCTSSCTSVPLAT | |
| SCHEMBL8525007 | 0.78 | MEN1 (0.53) | RAB9ATP53MEN1KMT2AKDM4E | |
| SCHEMBL17220063 | 0.78 | ROCK1 (0.53) | CTSKCTSLCTSSCTSB | |
| SCHEMBL17220301 | 0.78 | DHFR (0.45) | CTSKCTSLCTSSCTSBRAB9A | |
| SCHEMBL8525000 | 0.77 | TP53 (0.59) | CTSKCTSLCTSSCTSBRAB9A | |
| SCHEMBL17220267 | 0.76 | ROCK1 (0.55) | CTSKCTSLCTSSCTSBRAB9A | |
| SCHEMBL17220135 | 0.76 | RAB9A (0.40) | CTSKCTSLCTSSCTSBRAB9A | |
| SCHEMBL795403 | 0.75 | MAPT (0.38) | CTSKCTSLCTSSCTSBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-B1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2015-11-04 | — | — | EP | disclosed |