Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 6/20 | 0.39 |
| ▸ | CTSS | P25774 | 6/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CTSB | P07858 | 4/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 2/20 | 0.36 |
| ▸ | CTSH | P09668 | 2/20 | 0.36 |
| ▸ | CASP14 | P31944 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | CTSZ | Q9UBR2 | 2/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17220301 | 0.86 | DHFR (0.45) | RAB9ATSHRSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17220341 | 0.79 | LMNA (0.43) | RAB9ATSHRSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17220462 | 0.76 | MAPK1 (0.60) | CTSLCTSSCTSKCTSVPLAT | |
| SCHEMBL17219998 | 0.76 | CTSK (0.62) | RAB9ATSHRSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17220316 | 0.74 | NPC1 (0.42) | RAB9ATSHRSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL795403 | 0.73 | MAPT (0.38) | RAB9ATSHRSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17220307 | 0.71 | NPC1 (0.45) | RAB9ASMN1; SMN2KDM4ENPC1HSD17B10 | |
| SCHEMBL17220229 | 0.71 | DHFR (0.48) | RAB9ATSHRSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17219933 | 0.70 | CTSL (0.62) | NPC1CTSLCTSSCTSKCTSB | |
| SCHEMBL796672 | 0.68 | CTSK (0.61) | RAB9ATSHRSMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-B1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2015-11-04 | — | — | EP | disclosed |