Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 4/20 | 0.49 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 4/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 6/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13830973 | 0.89 | NOS2 (0.45) | IDH1ASIC3NOS3NOS2NOS1 | |
| SCHEMBL13623090 | 0.79 | ASIC3 (0.48) | IDH1ASIC3NOS3NOS2NOS1 | |
| SCHEMBL2476938 | 0.78 | KCNH2 (0.41) | NOS2NOS1 | |
| SCHEMBL17225282 | 0.77 | IDH1 (0.42) | IDH1ASIC3NOS3NOS2NOS1 | |
| SCHEMBL17615254 | 0.76 | NOS1 (0.46) | IDH1ASIC3NOS3NOS2NOS1 | |
| SCHEMBL1073895 | 0.76 | ASIC3 (0.68) | IDH1ASIC3NOS3NOS2NOS1 | |
| SCHEMBL14399309 | 0.76 | ASIC3 (0.48) | IDH1ASIC3NOS3NOS2NOS1 | |
| SCHEMBL29601960 | 0.76 | ASIC3 (0.68) | IDH1ASIC3NOS3NOS2NOS1 | |
| SCHEMBL14399310 | 0.76 | ASIC3 (0.48) | IDH1ASIC3NOS3NOS2NOS1 | |
| SCHEMBL13615803 | 0.75 | IDH1 (0.49) | IDH1ASIC3NOS3NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083412-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2016-03-24 | — | — | US | disclosed |
| US-9175031-B2 | Ketolide compounds | WOCKHARDT LIMITED (IN) | 2015-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083412-A1 | KETOLIDE COMPOUNDS | AKR1C3, AKR1D1, AKR1C1 | IDH1 1230/4885ASIC3 2108/4885NOS3 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.