Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.45 |
| ▸ | NOS3 | P29474 | 3/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 5/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17225307 | 0.89 | IDH1 (0.49) | NOS2NOS3IDH1BACE1APP | |
| SCHEMBL2476938 | 0.84 | KCNH2 (0.41) | NOS2NOS1CCR4 | |
| SCHEMBL25704869 | 0.80 | NOS1 (0.47) | NOS2NOS3IDH1BACE1APP | |
| SCHEMBL31508058 | 0.79 | BACE1 (0.42) | NOS2NOS3BACE1APPNOS1 | |
| SCHEMBL23582323 | 0.78 | PLA2G10 (0.43) | NOS2NOS3BACE1APPNOS1 | |
| SCHEMBL1912681 | 0.77 | MEN1 (0.47) | NOS2NOS3CCR4MPO | |
| SCHEMBL30376677 | 0.76 | — | — | |
| SCHEMBL91633 | 0.76 | — | — | |
| SCHEMBL12776106 | 0.75 | KCNH2 (0.38) | NOS2NOS1CCR4 | |
| SCHEMBL11955022 | 0.75 | CYP3A4 (0.42) | IDH1CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374017-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING PYRUVATE KINASE | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2023-11-23 | — | — | US | disclosed |
| US-20230374017-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING PYRUVATE KINASE | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2023-11-23 | — | — | US | disclosed |
| US-20220048922-A1 | COMPOUNDS TARGETING PRMT5 | ALIGOS THERAPEUTICS, INC. | 2022-02-17 | — | — | US | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9634268-B2 | Electronic device comprising metal complexes | MERCK PATENT GMBH (DE) | 2017-04-25 | — | — | US | disclosed |
| US-20120286254-A1 | ELECTRONIC DEVICE COMPRISING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120286254-A1 | ELECTRONIC DEVICE COMPRISING METAL COMPLEXES | AP1M1, EXOC1, EMC1 | NOS2 3487/4885NOS3 3669/4885IDH1 1219/4885 |
| US-20230374017-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING PYRUVATE KINASE | PCK1, PDK2, PDK1 | NOS2 3175/4885NOS3 2987/4885IDH1 642/4885 |
| US-20220048922-A1 | COMPOUNDS TARGETING PRMT5 | PRMT5, PRMT1, PRMT6 | NOS2 1181/4885NOS3 1631/4885IDH1 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.