Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722537 | 1.00 | NFE2L2 (0.56) | NFE2L2FBP1ENPP2P4HBMEN1 | |
| SCHEMBL2319221 | 0.82 | FBP1 (0.57) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL2319217 | 0.82 | FBP1 (0.57) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL10355224 | 0.82 | ENPP2 (0.51) | NFE2L2FBP1ENPP2MEN1LMNA | |
| SCHEMBL3594422 | 0.81 | RPS6KA3 (0.45) | NFE2L2FBP1ENPP2KDM4E | |
| SCHEMBL3594419 | 0.81 | RPS6KA3 (0.45) | NFE2L2FBP1ENPP2KDM4E | |
| SCHEMBL13790316 | 0.79 | NFE2L2 (0.82) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL9108500 | 0.79 | POLB (0.49) | NFE2L2NPSR1L3MBTL1 | |
| SCHEMBL9108496 | 0.79 | POLB (0.49) | NFE2L2NPSR1L3MBTL1 | |
| SCHEMBL14749829 | 0.78 | ENPP2 (0.47) | NFE2L2ENPP2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606824-B | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2023-03-14 | — | — | CN | claimed |
| CN-111606824-A | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2020-09-01 | — | — | CN | claimed |
| WO-2025099741-A1 | PROCESS FOR THE PREPARATION OF NITROSAMINE FREE CINACALCET AND SALTS THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2025-05-15 | — | — | WO | disclosed |
| CN-111606824-B | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2023-03-14 | — | — | CN | disclosed |
| EP-3164386-B1 | PIPERIDINONE HERBICIDES | FMC CORP (US) | 2020-10-07 | — | — | EP | disclosed |
| CN-111606824-A | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2020-09-01 | — | — | CN | disclosed |
| WO-2018184891-A1 | 4-SUBSTITUTED N-AMINO AND N-HYDROXY 2-OXO-PIPERIDINE-3-CARBOXAMIDE DERIVATIVES, SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-11 | — | — | WO | disclosed |
| WO-2018178010-A1 | N-CYCLOPROPYL-2-OXO-4-PHENYL-PIPERIDINE-3-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HERBICIDAL PLANT PROTECTION AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-04 | — | — | WO | disclosed |
| WO-2018178012-A1 | N-BENZYL-2-OXO-4-PHENYL-PIPERIDINE-3-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HERBICIDAL PLANT PROTECTION AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-04 | — | — | WO | disclosed |
| EP-2406211-B1 | A NEW METHOD FOR THE PREPARATION OF CINACALCET AND NEW INTERMEDIATES THEREOF | MEGAFINE PHARMA P LTD (IN) | 2018-06-27 | — | — | EP | disclosed |
| US-9944602-B2 | Piperidinone herbicides | FMC CORPORATION | 2018-04-17 | — | — | US | disclosed |
| EP-1915335-A2 | PROCESS FOR THE PREPARATION OF CINACALCET BASE | Teva Pharmaceutical Industries Ltd (IL) | 2008-04-30 | — | — | EP | disclosed |
| EP-1881954-A2 | PROCESS FOR PREPARING CINACALCET HYDROCHLORIDE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-01-30 | — | — | EP | disclosed |
| WO-2007127445-A2 | PROCESS FOR THE PREPARATION OF CINACALCET BASE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007127449-A1 | PROCESS FOR THE PREPARATION OF CINACALCET BASE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-11-08 | — | — | WO | disclosed |
| US-20070259964-A1 | Process for the preparation of cinacalcet base | TEVA PHARMACEUTICALS USA, INC. | 2007-11-08 | — | — | US | disclosed |
| US-20070260091-A1 | Process for the preparation of cinacalcet base | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-11-08 | — | — | US | disclosed |
| US-7250533-B2 | Process for preparing Cinacalcet hydrochloride | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2007-07-31 | — | — | US | disclosed |
| US-20070043243-A1 | Process for preparing Cinacalcet hydrochloride | TEVA PHARMACEUTICALS USA, INC. | 2007-02-22 | — | — | US | disclosed |
| WO-2006125026-A2 | PROCESS FOR PREPARING CINACALCET HYDROCHLORIDE | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259964-A1 | Process for the preparation of cinacalcet base | KRAS, CA9, CA4 | NFE2L2 3975/4885FBP1 2538/4885ENPP2 2342/4885 |
| US-20070260091-A1 | Process for the preparation of cinacalcet base | KRAS, CA9, SI | NFE2L2 4177/4885FBP1 2561/4885ENPP2 2293/4885 |
| US-20070043243-A1 | Process for preparing Cinacalcet hydrochloride | SI, PRCP, CA9 | NFE2L2 4160/4885FBP1 2546/4885ENPP2 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.