Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | GNA15 | P30679 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1351804 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL13948896 | 0.83 | ALDH1A1 (0.70) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL13948897 | 0.83 | MMP13 (0.56) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL13948890 | 0.81 | ALDH1A1 (0.55) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL23229951 | 0.78 | PRMT6 (0.59) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL24061764 | 0.78 | CHRM2 (0.60) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL13969804 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL29370584 | 0.73 | CHRM2 (0.68) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL297410 | 0.73 | CHRM2 (0.68) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL13948894 | 0.73 | MRGPRX4 (0.52) | KDM4EMEN1KMT2APRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720841-B1 | QUINAZOLINE DERIVATIVES AND THERAPEUTIC USE THEREOF | REXAHN PHARMACEUTICALS INC (US) | 2015-11-04 | — | — | EP | disclosed |