Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16979299 | 0.88 | THRB (0.49) | PPARDALDH1A1PPARGTHRB | |
| SCHEMBL14624909 | 0.88 | PPARD (0.50) | PPARDMAPTALDH1A1GAACRHBP | |
| SCHEMBL15773881 | 0.86 | MAPT (0.50) | PPARDMAPTALDH1A1GAACRHBP | |
| SCHEMBL26750219 | 0.82 | THRB (0.55) | PPARDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL17229442 | 0.81 | PPARA (0.43) | PPARDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL24293663 | 0.77 | THRB (0.40) | PPARDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10119273 | 0.77 | MMP14 (0.47) | PPARDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL622489 | 0.77 | MMP14 (0.47) | PPARDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL18502206 | 0.77 | ALDH1A1 (0.39) | PPARDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28690239 | 0.76 | MAOB (0.61) | MEN1KMT2ARAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150315012-A1 | LIGHT DRIVEN LIQUID CRYSTAL ELASTOMER ACTUATOR | ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-11-05 | — | — | US | disclosed |