SCHEMBL17229484

SCHEMBL17229484

CC1(C)c2cc3ccc4cccnc4c3nc2-c2c1cc(-c1ccc3ccccc3c1)c1cccnc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.36
CCR8 P51685 5/20 0.36
CCR5 P51681 3/20 0.36
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 2/20 0.35
GMNN O75496 1/20 0.35
TP53 P04637 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MMP2 P08253 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MMP9 P14780 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
MMP8 P22894 1/20 0.35
THPO P40225 1/20 0.35
MTOR P42345 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17229480 0.95 CCR1 (0.36) CCR1CCR8CCR5KDM4EMAPT
SCHEMBL17229489 0.90 KMT2A (0.34) CCR1CCR8LMNAHSP90AA1NPC1
SCHEMBL17229498 0.89 CCR1 (0.35) CCR1CCR8CCR5KDM4EMAPT
SCHEMBL17229516 0.88 KDM4E (0.33) CCR1CCR8KDM4EMAPTLMNA
SCHEMBL17229520 0.86 KDM4E (0.31) CCR1CCR8CCR5KDM4EMAPT
SCHEMBL17229487 0.85 ALDH1A1 (0.34) CCR1CCR8CCR5KDM4EMAPT
SCHEMBL17229496 0.85 ALDH1A1 (0.34) CCR1CCR8CCR5KDM4EMAPT
SCHEMBL17229479 0.84 ADORA2A (0.37) CCR1CCR8KDM4EMAPTTDP1
SCHEMBL17229517 0.82 RAB9A (0.34) NPC1RAB9A
SCHEMBL17229518 0.81 RAB9A (0.35) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-05 US disclosed
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, CCNA1 CCR1 258/4885CCR8 1347/4885CCR5 939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.