SCHEMBL17229489

SCHEMBL17229489

CC1(C)c2cc3ccccc3nc2-c2c1cc(-c1ccc3ccccc3c1)c1cccnc21

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34
CCR1 P32246 1/20 0.33
CCR8 P51685 1/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
TOP1 P11387 5/20 0.33
HSP90AA1 P07900 1/20 0.33
DHODH Q02127 4/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
MET P08581 1/20 0.32
HTR2B P41595 1/20 0.32
HTR5A P47898 1/20 0.32
LMNA P02545 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17229484 0.90 CCR1 (0.36) KMT2ACCR1CCR8NPC1POLB
SCHEMBL17229480 0.89 CCR1 (0.36) KMT2ACCR1CCR8NPC1POLB
SCHEMBL17229481 0.88 KMT2A (0.39) KMT2ANPC1RAB9ADHODHAKR1C3
SCHEMBL17229482 0.85 LMNA (0.33) NPC1POLBRAB9ATOP1HSP90AA1
SCHEMBL17229478 0.85 LMNA (0.33) KMT2ANPC1POLBRAB9ATOP1
SCHEMBL17229479 0.83 ADORA2A (0.37) KMT2ACCR1CCR8NPC1POLB
SCHEMBL17229516 0.83 KDM4E (0.33) CCR1CCR8TOP1DHODHLMNA
SCHEMBL17229498 0.80 CCR1 (0.35) KMT2ACCR1CCR8NPC1POLB
SCHEMBL17229520 0.80 KDM4E (0.31) CCR1CCR8HSP90AA1LMNA
SCHEMBL17229518 0.78 RAB9A (0.35) NPC1RAB9AMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-05 US disclosed
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, CCNA1 KMT2A 2505/4885CCR1 258/4885CCR8 1347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.