SCHEMBL17229486

SCHEMBL17229486

c1ccc(C2(c3ccccc3)c3cc4ccc5ccccc5c4nc3-c3c2cc(-c2ccc4ccccc4c2)c2cccnc32)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
CCR1 P32246 3/20 0.32
CCR8 P51685 3/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GPR84 Q9NQS5 1/20 0.31
HTR2B P41595 1/20 0.31
HTR5A P47898 1/20 0.31
LMNA P02545 2/20 0.31
MAPK9 P45984 2/20 0.30
MAPK10 P53779 2/20 0.30
PIK3CD O00329 1/20 0.30
AKT1 P31749 1/20 0.30
DHFR P00374 1/20 0.30
MAPK8 P45983 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
TP53 P04637 1/20 0.30
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17229496 0.95 ALDH1A1 (0.34) ALDH1A1ADORA2AADORA1CCR1CCR8
SCHEMBL17229490 0.90 ALDH1A1 (0.34) ALDH1A1ADORA2AADORA1CCR1CCR8
SCHEMBL17229482 0.90 LMNA (0.33) ALDH1A1ADORA2AADORA1GPR84HTR2B
SCHEMBL17229492 0.87 ALDH1A1 (0.33) ALDH1A1CCR1CCR8L3MBTL1LMNA
SCHEMBL17229480 0.85 CCR1 (0.36) ALDH1A1ADORA2AADORA1CCR1CCR8
SCHEMBL17229475 0.85 ADORA2A (0.37) ALDH1A1ADORA2AADORA1GPR84HTR2B
SCHEMBL17229487 0.84 ALDH1A1 (0.34) ALDH1A1ADORA2AADORA1CCR1CCR8
SCHEMBL17229521 0.84 TOP1 (0.36) ALDH1A1KDM4EGMNNTP53CYP3A4
SCHEMBL17229514 0.84 TOP1 (0.34) HSP90AA1
SCHEMBL17229507 0.80 ALDH1A1 (0.35) ALDH1A1AKT1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-05 US disclosed
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, CCNA1 ALDH1A1 480/4885ADORA2A 4594/4885ADORA1 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.