SCHEMBL17229482

SCHEMBL17229482

c1ccc(C2(c3ccccc3)c3cc4ccccc4nc3-c3c2cc(-c2ccc4ccccc4c2)c2cccnc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
TOP1 P11387 6/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
RAB9A P51151 1/20 0.32
AKT1 P31749 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GPR84 Q9NQS5 1/20 0.31
HTR2B P41595 1/20 0.31
HTR5A P47898 1/20 0.31
HSP90AA1 P07900 1/20 0.31
MAPK9 P45984 1/20 0.30
MAPK10 P53779 1/20 0.30
PIK3CD O00329 1/20 0.30
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17229496 0.91 ALDH1A1 (0.34) LMNAADORA2AADORA1AKT1ALDH1A1
SCHEMBL17229478 0.90 LMNA (0.33) LMNATOP1ADORA2AADORA1NPC1
SCHEMBL17229486 0.90 ALDH1A1 (0.34) LMNAADORA2AADORA1AKT1ALDH1A1
SCHEMBL17223560 0.88 ADORA2A (0.37) ADORA2AADORA1NPC1RAB9AAKT1
SCHEMBL17229521 0.88 TOP1 (0.36) TOP1NPC1RAB9AALDH1A1
SCHEMBL17229514 0.86 TOP1 (0.34) TOP1HSP90AA1
SCHEMBL17229489 0.85 KMT2A (0.34) LMNATOP1ADORA2AADORA1NPC1
SCHEMBL17229475 0.85 ADORA2A (0.37) TOP1ADORA2AADORA1AKT1ALDH1A1
SCHEMBL17229492 0.81 ALDH1A1 (0.33) LMNATOP1ALDH1A1HSP90AA1
SCHEMBL17229487 0.80 ALDH1A1 (0.34) LMNAADORA2AADORA1AKT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-05 US disclosed
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150318490-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, CCNA1 LMNA 1670/4885TOP1 655/4885ADORA2A 4594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.