Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17235974 | 0.93 | TK1 (0.51) | TK1POLB | |
| SCHEMBL16217854 | 0.93 | TK1 (0.51) | TK1POLB | |
| SCHEMBL27062465 | 0.92 | P2RY1 (0.36) | TK1P2RY1POLB | |
| SCHEMBL16410980 | 0.90 | POLB (0.47) | P2RY1POLB | |
| SCHEMBL16217852 | 0.89 | POLG (0.40) | TK1POLB | |
| SCHEMBL27062479 | 0.89 | TK1 (0.42) | TK1P2RY1POLB | |
| SCHEMBL16221824 | 0.88 | POLB (0.50) | P2RY1POLB | |
| SCHEMBL18158912 | 0.88 | POLB (0.50) | P2RY1POLB | |
| SCHEMBL26276583 | 0.86 | TK1 (0.47) | TK1POLB | |
| SCHEMBL16217855 | 0.84 | TERT (0.50) | P2RY1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015168635-A2 | COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2015-11-05 | — | — | WO | disclosed |