SCHEMBL17238684

SCHEMBL17238684

CCCCCOc1c(Cl)c(Cl)c(C#N)c(C#N)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 4/20 0.36
THRB P10828 4/20 0.36
HPGD P15428 5/20 0.35
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 3/20 0.35
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PLA2G2A P14555 1/20 0.33
NR5A1 Q13285 1/20 0.33
SRC P12931 1/20 0.32
GAA P10253 1/20 0.32
LTA4H P09960 1/20 0.32
LPAR2 Q9HBW0 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683865 0.81 THRA (0.43) THRATHRBALDH1A1TP53SMN1; SMN2
SCHEMBL21091617 0.80 NR5A1 (0.38) THRATHRBHPGDALDH1A1KDM4E
SCHEMBL9685144 0.79 THRA (0.45) THRATHRBALDH1A1TP53PLA2G2A
SCHEMBL9683159 0.79 THRA (0.45) THRATHRBALDH1A1TP53PLA2G2A
SCHEMBL9684013 0.79 THRA (0.45) THRATHRBALDH1A1TP53PLA2G2A
SCHEMBL9683839 0.79 THRA (0.45) THRATHRBALDH1A1TP53PLA2G2A
SCHEMBL9683858 0.79 THRA (0.45) THRATHRBALDH1A1TP53PLA2G2A
SCHEMBL18190896 0.76 THRB (0.35) THRATHRBHPGDALDH1A1MAPT
SCHEMBL3892887 0.75 AR (0.36) THRATHRBHPGDALDH1A1KDM4E
SCHEMBL9683985 0.75 NPC1 (0.44) THRATHRBKDM4ECYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279186-B Compound, photosensitive resin composition comprising same and color filter 三星SDI株式会社 2020-03-31 CN disclosed
CN-106588938-B Compound, photosensitive resin composition comprising same and color filter 三星SDI株式会社 2019-12-17 CN disclosed
CN-105085535-B Dye composition and mixture, photosensitive resin composition and colored filter 三星SDI株式会社 2018-03-06 CN disclosed
US-9815843-B2 Compound, photosensitive resin composition comprising the same, and color filter SAMSUNG SDI CO., LTD. (KR) 2017-11-14 US disclosed
US-20170107224-A1 Novel Compound, Photosensitive Resin Composition Comprising the Same, and Color Filter SAMSUNG SDI CO., LTD. (KR) 2017-04-20 US disclosed
US-9581729-B2 Compound, photosensitive resin composition comprising the same and color filter SAMSUNG SDI CO., LTD. (KR) 2017-02-28 US disclosed
US-20160377764-A1 Novel Compound, Photosensitive Resin Composition Comprising the Same and Color Filter SAMSUNG SDI CO., LTD. (KR) 2016-12-29 US disclosed
US-9242990-B2 Compound, novel mixture, photosensitive resin composition, and color filter SAMSUNG SDI CO., LTD. (KR) 2016-01-26 US disclosed
US-20150322077-A1 Novel Compound, Novel Mixture, Photosensitive Resin Composition, and Color Filter SAMSUNG SDI CO., LTD. (KR) 2015-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170107224-A1 Novel Compound, Photosensitive Resin Composition Comprising the Same, and Color Filter RB1, SUN2, ASIC1 THRA 4694/4885THRB 4841/4885HPGD 3023/4885
US-20160377764-A1 Novel Compound, Photosensitive Resin Composition Comprising the Same and Color Filter RB1, TAS1R1, ASIC1 THRA 4704/4885THRB 4846/4885HPGD 2445/4885
US-20150322077-A1 Novel Compound, Novel Mixture, Photosensitive Resin Composition, and Color Filter RB1, TAS1R1, SUN2 THRA 4705/4885THRB 4822/4885HPGD 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.