Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17242344 | 0.84 | ALDH1A1 (0.42) | ALOX5APFEN1P2RX3SCN9AADRA1D | |
| SCHEMBL17241848 | 0.84 | ALOX5AP (0.43) | ALOX5APFEN1SCN9A | |
| SCHEMBL1137123 | 0.80 | KDR (0.42) | KDM4CP2RX3SCN9ABRD4SCN5A | |
| SCHEMBL18921106 | 0.77 | MEN1 (0.52) | ALOX5APFEN1PDE10ALMNASMN1; SMN2 | |
| SCHEMBL17242285 | 0.76 | P2RX3 (0.41) | ALOX5APFEN1P2RX3SCN9ASMN1; SMN2 | |
| SCHEMBL2789425 | 0.72 | NNMT (0.46) | ALOX5APFEN1ADRA1DADRA1AADRA1B | |
| SCHEMBL27865966 | 0.71 | NPC1 (0.41) | ALOX5APFEN1P2RX3SCN9ASCN5A | |
| SCHEMBL2025625 | 0.69 | DDR2 (0.52) | — | |
| SCHEMBL4329985 | 0.69 | ALDH1A1 (0.56) | PDE10ALMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL30473086 | 0.69 | ALDH1A1 (0.56) | PDE10ALMNAPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015169180-A1 | SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-11-12 | — | — | WO | disclosed |