Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033187 | 0.82 | MAPT (0.51) | GAALMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11212890 | 0.79 | KMT2A (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17244020 | 0.79 | WDR5 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11045544 | 0.79 | CA2 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3176485 | 0.76 | LMNA (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10851561 | 0.76 | RAB9A (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17243795 | 0.75 | LMNA (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9274238 | 0.75 | KMT2A (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14839650 | 0.75 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11212886 | 0.75 | CA12 (0.52) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181229-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |