Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721863 | 0.79 | KMT2A (0.49) | POLBLMNAPRNPKMT2AALDH1A1 | |
| SCHEMBL10851561 | 0.79 | RAB9A (0.57) | POLBHIF1ACA12CA1CA2 | |
| SCHEMBL3176485 | 0.79 | LMNA (0.62) | POLBCA12CA1CA2CA7 | |
| SCHEMBL11212890 | 0.79 | KMT2A (0.57) | POLBCA12CA1CA2CA7 | |
| SCHEMBL22232434 | 0.78 | MRGPRX4 (0.49) | POLBLMNAMAPTKDM4EKMT2A | |
| SCHEMBL13472196 | 0.78 | TRPM8 (0.53) | HIF1ALMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL11212886 | 0.78 | CA12 (0.52) | POLBHIF1ACA12CA1CA2 | |
| SCHEMBL14839650 | 0.78 | CA12 (0.52) | POLBHIF1ACA12CA1CA2 | |
| SCHEMBL9274238 | 0.78 | KMT2A (0.56) | POLBCA12CA1CA2CA7 | |
| SCHEMBL14830177 | 0.77 | ALDH1A1 (0.47) | CA2LMNAMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181229-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-9181229-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |