Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16241974 | 0.86 | LMNA (0.50) | CA1CA2CA12CA9CA14 | |
| SCHEMBL23414073 | 0.86 | L3MBTL1 (0.40) | CA1CA2CA12CA9CA14 | |
| SCHEMBL6115595 | 0.85 | RECQL (0.39) | CA1CA2CA12CA9CA14 | |
| SCHEMBL8401684 | 0.85 | RECQL (0.39) | CA1CA2CA12CA9CA14 | |
| SCHEMBL2011456 | 0.84 | CA1 (0.42) | CA1CA2CA12CA9CA14 | |
| SCHEMBL14785200 | 0.84 | CA1 (0.42) | CA1CA2CA12CA9CA14 | |
| SCHEMBL355847 | 0.81 | GAA (0.44) | CA1CA2CA12CA9CA14 | |
| SCHEMBL591090 | 0.80 | CES2 (0.55) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL17864532 | 0.79 | NR1H4 (0.47) | CA1CA2CA12CA9CA14 | |
| SCHEMBL17374982 | 0.79 | EGFR (0.47) | CA1CA2CA12CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015170775-A1 | SUBSTITUTED AZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES | 日産化学工業株式会社 | 2015-11-12 | — | — | WO | disclosed |