Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6115595 | 1.00 | RECQL (0.39) | RECQLCA12CA1CA2CA9 | |
| SCHEMBL17253286 | 0.85 | CA1 (0.40) | CA12CA1CA2CA9CA14 | |
| SCHEMBL406864 | 0.84 | KDM4E (0.47) | RECQLCA12CA1CA2CA9 | |
| SCHEMBL8401255 | 0.84 | KDM4E (0.47) | RECQLCA12CA1CA2CA9 | |
| SCHEMBL406865 | 0.84 | KDM4E (0.47) | RECQLCA12CA1CA2CA9 | |
| SCHEMBL23414073 | 0.81 | L3MBTL1 (0.40) | CA12CA1CA2CA9CA14 | |
| SCHEMBL16241974 | 0.81 | LMNA (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL9902629 | 0.77 | KDM1A (0.42) | RECQLKDM1ARAB9AHTTLMNA | |
| SCHEMBL19014876 | 0.77 | KDM1A (0.42) | RECQLKDM1ARAB9AHTTLMNA | |
| SCHEMBL355847 | 0.76 | GAA (0.44) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2738168-B1 | N-HETERO-RING-SUBSTITUTED AMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2016-04-06 | — | — | EP | disclosed |
| US-9006273-B2 | N-hetero-ring-substituted amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-04-14 | — | — | US | disclosed |
| US-9006273-B2 | N-hetero-ring-substituted amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-04-14 | — | — | US | disclosed |
| US-20140221437-A1 | N-HETERO-RING-SUBSTITUTED AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20140221437-A1 | N-HETERO-RING-SUBSTITUTED AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-08-07 | — | — | US | disclosed |
| EP-2738168-A1 | N-HETERO-RING-SUBSTITUTED AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8722711-B2 | Acylbenzene derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722711-B2 | Acylbenzene derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8557802-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-10-15 | — | — | US | disclosed |
| US-8557802-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-10-15 | — | — | US | disclosed |
| US-20130217733-A1 | ACYLBENZENE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-08-22 | — | — | US | disclosed |
| US-20130217733-A1 | ACYLBENZENE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-08-22 | — | — | US | disclosed |
| EP-2463279-A1 | AMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-20120129832-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-24 | — | — | US | disclosed |
| US-20120129832-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129832-A1 | AMIDE DERIVATIVE | SLC5A1, SLC5A2, SLC2A1 | RECQL 3435/4885CA12 1565/4885CA1 983/4885 |
| US-20130217733-A1 | ACYLBENZENE DERIVATIVE | AMY2A, IAPP, SLC5A1 | RECQL 4546/4885CA12 951/4885CA1 1152/4885 |
| US-20140221437-A1 | N-HETERO-RING-SUBSTITUTED AMIDE DERIVATIVE | IAPP, AMY2A, GPR119 | RECQL 2669/4885CA12 2254/4885CA1 944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.