Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15921407 | 0.80 | ERN1 (0.43) | ERN1ALDH1A1HPGDAGPAT2SLC9A1 | |
| SCHEMBL4158464 | 0.75 | SMN1; SMN2 (0.43) | ERN1ALDH1A1HPGDAGPAT2KDM4E | |
| SCHEMBL4924977 | 0.74 | ALDH1A1 (0.44) | ERN1ALDH1A1HPGDSLC9A1KDM4E | |
| SCHEMBL29320708 | 0.74 | KMT2A (0.36) | ERN1ALDH1A1KMT2ATDP1MAPT | |
| SCHEMBL7699644 | 0.72 | ALDH1A1 (0.56) | ERN1ALDH1A1HPGDAGPAT2KDM4E | |
| SCHEMBL4151708 | 0.71 | ERN1 (0.42) | ERN1ALDH1A1HPGDSLC9A1KDM4E | |
| SCHEMBL4924013 | 0.70 | ALDH1A1 (0.41) | ERN1ALDH1A1HPGDSLC9A1KDM4E | |
| SCHEMBL24438161 | 0.70 | AGPAT2 (0.60) | ERN1ALDH1A1HPGDAGPAT2TSHR | |
| SCHEMBL1700335 | 0.70 | SLC6A3 (0.46) | ALDH1A1HPGDKDM4EPOLBLMNA | |
| SCHEMBL4914496 | 0.69 | ALDH1A1 (0.40) | ERN1ALDH1A1HPGDSLC9A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493430-B2 | Biaryl- or heterocyclic biaryl-substituted cyclohexene derivative compounds as CETP inhibitors | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2016-11-15 | — | — | US | disclosed |
| US-20160237046-A9 | Biaryl- or Heterocyclic Biaryl-Substituted Cyclohexene Derivative Compounds as CETP Inhibitors | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2016-08-18 | — | — | US | disclosed |
| US-20150322023-A1 | Biaryl- or Heterocyclic Biaryl-Substituted Cyclohexene Derivative Compounds as CETP Inhibitors | CHONG KUN DANG PHARM CORP (KR) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237046-A9 | Biaryl- or Heterocyclic Biaryl-Substituted Cyclohexene Derivative Compounds as CETP Inhibitors | CETP, LIPC, PCSK9 | ERN1 1925/4885ALDH1A1 3741/4885HPGD 1646/4885 |
| US-20150322023-A1 | Biaryl- or Heterocyclic Biaryl-Substituted Cyclohexene Derivative Compounds as CETP Inhibitors | CETP, LIPC, PCSK9 | ERN1 1925/4885ALDH1A1 3741/4885HPGD 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.