Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | PRNP | P04156 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | AGPAT2 | O15120 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20692608 | 0.91 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDUSP2PRNP | |
| SCHEMBL8818026 | 0.84 | ALPL (0.49) | ALDH1A1KDM4EHPGDUSP2PRNP | |
| SCHEMBL12056630 | 0.84 | NR3C1 (0.46) | ALDH1A1KDM4EHPGDUSP2PRNP | |
| SCHEMBL29634149 | 0.83 | PTGDR2 (0.57) | ALDH1A1KDM4EHPGDUSP2PRNP | |
| SCHEMBL3759371 | 0.83 | PTGDR2 (0.57) | ALDH1A1KDM4EHPGDUSP2PRNP | |
| SCHEMBL399421 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDTDP1RECQL | |
| SCHEMBL701921 | 0.83 | ACHE (0.47) | ALDH1A1KDM4EHPGDUSP2PRNP | |
| SCHEMBL27985519 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDUSP2PRNP | |
| SCHEMBL2127233 | 0.82 | TRPV4 (0.55) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL29636402 | 0.82 | TRPV4 (0.55) | ALDH1A1HSD17B10MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342504-B1 | PEPTIDES AS ANTITHROMBINS AND ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2002-01-29 | — | — | US | disclosed |
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| EP-0000507-A1 | Process for the production of hydrogels in the form of spherically shaped beads with larger diameters | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |