Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696523 | 0.91 | TRPV4 (0.39) | ALDH1A1HPGDKDM4ERAB9APOLB | |
| SCHEMBL6569016 | 0.75 | CYP2A6 (0.33) | ALDH1A1POLBPTGS2PTGS1PGR | |
| SCHEMBL8914993 | 0.74 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL6068893 | 0.71 | HDAC4 (0.42) | ALDH1A1KDM4EPTGS2PGRDRD2 | |
| SCHEMBL17254341 | 0.70 | ERN1 (0.48) | ALDH1A1HPGDKDM4ERAB9APOLB | |
| SCHEMBL7363820 | 0.70 | PDE4A (0.50) | — | |
| SCHEMBL2752719 | 0.70 | DRD2 (0.31) | DRD2DRD4DRD3 | |
| SCHEMBL4160550 | 0.69 | PTGS2 (0.41) | PTGS2PTGS1DRD2DRD4DRD3 | |
| SCHEMBL4158464 | 0.68 | SMN1; SMN2 (0.43) | ALDH1A1HPGDKDM4ERAB9APOLB | |
| SCHEMBL4924977 | 0.68 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4ERAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | GLAXO GROUP LIMITED (GB) | 2008-09-25 | — | — | US | disclosed |
| EP-1670764-A1 | CYCLOHEXENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005037794-A1 | CYCLOHEXENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | C1R, CYP1B1, CYP2C9 | ALDH1A1 2527/4885HPGD 2218/4885KDM4E 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.