Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255352 | 0.92 | ALPL (0.50) | AMY1AALPLMEN1NPC1RAB9A | |
| SCHEMBL17255144 | 0.90 | AMY1A (0.60) | AMY1AALPLMEN1NPC1RAB9A | |
| SCHEMBL17255247 | 0.87 | AMY1A (0.48) | AMY1AALPLMEN1NPC1RAB9A | |
| SCHEMBL17255264 | 0.87 | ALPL (0.43) | AMY1AALPLMEN1NPC1RAB9A | |
| SCHEMBL17268669 | 0.86 | CBFB (0.43) | AMY1AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL17255257 | 0.86 | NPC1 (0.51) | AMY1AALPLMEN1NPC1RAB9A | |
| SCHEMBL17255215 | 0.85 | AMY1A (0.50) | AMY1AALPLMEN1NPC1RAB9A | |
| SCHEMBL17255182 | 0.84 | AMY1A (0.60) | AMY1AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL17255229 | 0.84 | RAB9A (0.56) | AMY1AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL17255253 | 0.84 | ALPL (0.46) | AMY1AALPLMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-19 | — | — | US | claimed |
| EP-2944635-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2015-11-18 | — | — | EP | claimed |
| US-9951049-B2 | Pyrazole linked benzimidazole conjugates and a process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |
| US-9951049-B2 | Pyrazole linked benzimidazole conjugates and a process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-19 | — | — | US | disclosed |
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-19 | — | — | US | disclosed |
| EP-2944635-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2015-11-18 | — | — | EP | disclosed |
| EP-2944635-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2015-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | BRDT, MCL1, MGST3 | AMY1A 4542/4885ALPL 3575/4885MEN1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.