SCHEMBL17255264

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17255248	0.90	AMY1A (0.53)	CACNA1DAMY1APDPK1MEN1NPC1
	SCHEMBL17255352	0.90	ALPL (0.50)	ALPLAMY1APDE2APDPK1MEN1
	SCHEMBL17255255	0.87	AMY1A (0.50)	ALPLAMY1APDE2APDPK1MEN1
	SCHEMBL17268693	0.87	CBFB (0.39)	AMY1AKDM4EFOXO1NPBWR1
	SCHEMBL17255241	0.85	RAB9A (0.52)	MEN1NPC1MAPTRAB9AKMT2A
	SCHEMBL17255247	0.85	AMY1A (0.48)	ALPLAMY1APDE2APDPK1MEN1
	SCHEMBL17255338	0.83	AMY1A (0.43)	ALPLAMY1APDE2APDPK1MEN1
	SCHEMBL17255217	0.83	NPBWR1 (0.42)	AMY1APDPK1NPC1MAPTRAB9A
	SCHEMBL17255257	0.83	NPC1 (0.51)	ALPLAMY1APDE2APDPK1MEN1
	SCHEMBL17255252	0.82	SMN1; SMN2 (0.41)	AMY1APDPK1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.