Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 4/20 | 0.37 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726750 | 0.83 | MEN1 (0.48) | UBE2MDCUN1D1CCR2 | |
| SCHEMBL1726693 | 0.79 | MCHR1 (0.38) | ACHE | |
| SCHEMBL1844021 | 0.77 | WNK1 (0.43) | DRD2DRD4DRD3UBE2MDCUN1D1 | |
| SCHEMBL1726870 | 0.75 | LSS (0.34) | UBE2MDCUN1D1LSSCCR2WNK1 | |
| SCHEMBL1844023 | 0.74 | MEN1 (0.53) | DRD2DRD4UBE2MDCUN1D1LSS | |
| SCHEMBL1463161 | 0.69 | PROKR1 (0.35) | PROKR1 | |
| SCHEMBL16494664 | 0.69 | PROKR1 (0.35) | PROKR1 | |
| SCHEMBL12482193 | 0.69 | OPRM1 (0.42) | LSSACHE | |
| SCHEMBL1727312 | 0.67 | MCHR1 (0.44) | ACHE | |
| SCHEMBL12153529 | 0.67 | MCHR1 (0.44) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10034476-B2 | Insecticidal phenyl-or pyridyl-piperdine compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2018-07-31 | — | — | US | disclosed |
| US-20170347650-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-07 | — | — | US | disclosed |
| US-9808006-B2 | Insecticidal phenyl-or pyridyl-piperdine compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-07 | — | — | US | disclosed |
| US-20130317062-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-28 | — | — | US | disclosed |
| US-8518971-B2 | Insecticidal phenyl- or pyridyl-piperdine compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| WO-2012037282-A3 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| EP-2324010-B1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-11-30 | — | — | EP | disclosed |
| US-20110136866-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERDINE COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10034476-B2 | Insecticidal phenyl-or pyridyl-piperdine compounds | ACHE, CHRM1, CHRM2 | DRD2 377/4885DRD4 795/4885DRD3 573/4885 |
| US-20130317062-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | ACHE, CHRM1, CHRM2 | DRD2 377/4885DRD4 795/4885DRD3 573/4885 |
| US-20110136866-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERDINE COMPOUNDS | ACHE, CHRM1, CHRM2 | DRD2 336/4885DRD4 666/4885DRD3 533/4885 |
| US-20170347650-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | ACHE, CHRM1, CHRM2 | DRD2 377/4885DRD4 795/4885DRD3 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.