Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782292 | 0.94 | CTSS (0.35) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL1725614 | 0.81 | MCL1 (0.39) | — | |
| SCHEMBL1742306 | 0.79 | AKT1 (0.38) | ALDH1A1 | |
| SCHEMBL782399 | 0.79 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL4918504 | 0.76 | CA14 (0.37) | — | |
| SCHEMBL9893327 | 0.75 | PHF8 (0.39) | CTSSCTSLCTSBALDH1A1 | |
| SCHEMBL13254363 | 0.75 | PHF8 (0.34) | CTSSCTSLCTSB | |
| SCHEMBL182386 | 0.73 | ALDH1A1 (0.41) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL6534709 | 0.72 | HDAC6 (0.33) | CTSSCTSLCTSBALDH1A1 | |
| SCHEMBL9945620 | 0.71 | PHF8 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070856-A1 | CROSS-LINKING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070856-A1 | CROSS-LINKING AGENTS | ORC3, TXN, PROC | CTSS 4215/4885CTSL 4328/4885CTSB 4397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.