Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28285055 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MEN1CYP2C19RECQLKMT2A | |
| SCHEMBL11735656 | 0.77 | MGAM (0.39) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28098443 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MEN1CYP2C19RECQLKMT2A | |
| Butane SCHEMBL17256453 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MEN1CYP2C19RECQLKMT2A | |
| SCHEMBL3444201 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1260957 | 0.72 | FFAR3 (0.36) | ALDH1A1CYP2C19 | |
| SCHEMBL2475483 | 0.71 | DGAT1 (0.44) | ALDH1A1CYP2C19 | |
| SCHEMBL7059566 | 0.69 | CYP4F2 (0.33) | CYP2C19 | |
| SCHEMBL779254 | 0.69 | ALDH1A1 (0.38) | ALDH1A1CYP2C19RECQLKMT2A | |
| SCHEMBL13785298 | 0.67 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996696-A | Prevention, reduction or improvement of odor of elderly people | 弗门尼舍有限公司 | 2023-04-21 | — | — | CN | claimed |
| CN-118317958-A | Tri-fused ring derivative and preparation method and application thereof | 上海济煜医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| US-20230301970-A1 | CARBOXAMIDE DERIVATIVES | NOVARTIS PHARMACEUTICALS UK LIMITED (GB) | 2023-09-28 | — | — | US | disclosed |
| US-11672782-B2 | Carboxamide derivatives | NOVARTIS AG (CH) | 2023-06-13 | — | — | US | disclosed |
| EP-3143018-B1 | CARBOXAMIDE DERIVATIVES | NOVARTIS AG (CH) | 2021-03-10 | — | — | EP | disclosed |
| US-20210052554-A1 | CARBOXAMIDE DERIVATIVES | NOVARTIS PHARMACEUTICALS UK LIMITED (GB) | 2021-02-25 | — | — | US | disclosed |
| US-20200268718-A1 | CARBOXAMIDE DERIVATIVES | NOVARTIS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| US-10195181-B2 | Carboxamide derivatives | NOVARTIS AG (CH) | 2019-02-05 | — | — | US | disclosed |
| CN-106661012-A | Carboxamide derivatives | 诺华股份有限公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-3143018-A1 | CARBOXAMIDE DERIVATIVES | Novartis AG (CH) | 2017-03-22 | — | — | EP | disclosed |
| US-20170014388-A1 | CARBOXAMIDE DERIVATIVES | NOVARTIS AG (CH) | 2017-01-19 | — | — | US | disclosed |
| US-9403810-B2 | Carboxamide derivatives | NOVARTIS AG (CH) | 2016-08-02 | — | — | US | disclosed |
| US-20150329529-A1 | CARBOXAMIDE DERIVATIVES | NOVARTIS AG (CH) | 2015-11-19 | — | — | US | disclosed |
| WO-2015175796-A1 | CARBOXAMIDE DERIVATIVES | NOVARTIS AG (CH) | 2015-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052554-A1 | CARBOXAMIDE DERIVATIVES | SIRT5, SIRT7, ADCY5 | ALDH1A1 350/4885MEN1 1189/4885CYP2C19 46/4885 |
| US-20230301970-A1 | CARBOXAMIDE DERIVATIVES | SIRT1, ADCY5, ASIC1 | ALDH1A1 183/4885MEN1 1002/4885CYP2C19 58/4885 |
| US-20150329529-A1 | CARBOXAMIDE DERIVATIVES | SIRT5, SIRT7, ADCY5 | ALDH1A1 350/4885MEN1 1189/4885CYP2C19 46/4885 |
| US-11672782-B2 | Carboxamide derivatives | SIRT5, SIRT7, ADCY5 | ALDH1A1 350/4885MEN1 1189/4885CYP2C19 46/4885 |
| US-20200268718-A1 | CARBOXAMIDE DERIVATIVES | SIRT5, SIRT7, ADCY5 | ALDH1A1 350/4885MEN1 1189/4885CYP2C19 46/4885 |
| US-20170014388-A1 | CARBOXAMIDE DERIVATIVES | SIRT5, SIRT7, ADCY5 | ALDH1A1 350/4885MEN1 1189/4885CYP2C19 46/4885 |
| US-10195181-B2 | Carboxamide derivatives | SIRT5, SIRT7, ADCY5 | ALDH1A1 350/4885MEN1 1189/4885CYP2C19 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.