SCHEMBL17258696

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30468495	0.83	ALDH1A1 (0.51)	ALDH1A1HTTTSHRNR3C1POLB
	SCHEMBL1291364	0.83	ALDH1A1 (0.51)	ALDH1A1HTTTSHRNR3C1POLB
	SCHEMBL3061461	0.82	PTPN1 (0.36)	ALDH1A1HTTPTPN1CA2KMT2A
	SCHEMBL21048806	0.81	ALDH1A1 (0.46)	ALDH1A1HTTTSHRNR3C1RORC
	SCHEMBL21048811	0.78	CYP3A4 (0.47)	ALDH1A1HTTTSHRRORCPOLB
	SCHEMBL31652674	0.77	PTPN1 (0.36)	ALDH1A1HTTPOLBKDM4EGAA
	SCHEMBL17258804	0.77	HCRTR1 (0.40)	ALDH1A1HTTPOLBMAPTKDM4E
	SCHEMBL1627549	0.77	PTPN1 (0.36)	ALDH1A1HTTPOLBKDM4EGAA
	SCHEMBL17258750	0.76	ALDH1A1 (0.41)	ALDH1A1HTTTSHRNR3C1RORC
	SCHEMBL21048901	0.75	PTGS2 (0.36)	ALDH1A1HTTMAPTPTPN1USP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.