Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2892311 | 0.83 | C5AR1 (0.53) | ALDH1A1HTTKDM4EKEAP1LMNA | |
| SCHEMBL17258696 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HTTKDM4ERORCLMNA | |
| SCHEMBL21048757 | 0.78 | KEAP1 (0.45) | CYP3A4CYP2C9CYP2C19TAS2R14KDM4E | |
| SCHEMBL21048806 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HTTKDM4ERORCHPGD | |
| SCHEMBL5853978 | 0.72 | TEAD1 (0.49) | CYP3A4CYP2C9CYP2C19ALDH1A1APOBEC3G | |
| SCHEMBL5853971 | 0.72 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19ALDH1A1APOBEC3G | |
| SCHEMBL16550141 | 0.72 | APOBEC3G (0.52) | CYP3A4CYP2C9CYP2C19ALDH1A1APOBEC3G | |
| SCHEMBL16539764 | 0.70 | ALDH1A1 (0.41) | CYP3A4CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL29827525 | 0.69 | TSHR (0.48) | CYP3A4CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL8974476 | 0.69 | ALDH1A1 (0.46) | CYP3A4CYP2C9CYP2C19ALDH1A1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143021-B1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER (US) | 2019-06-12 | — | — | EP | disclosed |