Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26697692 | 0.98 | NCF1 (0.52) | NCF1MAPTHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL27697571 | 0.86 | HSP90AA1 (0.44) | NCF1MAPTHSP90AA1HSP90AB1ALDH1A1 | |
| Water SCHEMBL27717949 | 0.84 | HSP90AA1 (0.42) | NCF1MAPTHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL825817 | 0.84 | MAPT (0.54) | NCF1MAPTHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL16381310 | 0.77 | NR4A2 (0.48) | NCF1MAPTHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL30906615 | 0.76 | KDM4E (0.50) | NCF1MAPTHSP90AA1ALDH1A1MEN1 | |
| 8-Aminoquinoline SCHEMBL860459 | 0.75 | LMNA (0.53) | NCF1MAPTHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL4554547 | 0.74 | PSMD14 (0.56) | NCF1MAPTHSP90AA1ALDH1A1MEN1 | |
| SCHEMBL204153 | 0.74 | KDM4E (0.44) | NCF1MAPTHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL3350823 | 0.74 | NCF1 (0.60) | NCF1MAPTHSP90AA1HSP90AB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615537-A2 | 6-6 FUSED BICYCLIC HETEROARYL COMPOUNDS AND THEIR USE AS LATS INHIBITORS | Novartis AG (CH) | 2020-03-04 | — | — | EP | claimed |
| WO-2018198077-A2 | 6-6 FUSED BICYCLIC HETEROARYL COMPOUNDS AND THEIR USE AS LATS INHIBITORS | NOVARTIS AG (CH) | 2018-11-01 | — | — | WO | claimed |
| EP-2699572-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Origenis GmbH (DE) | 2014-02-26 | — | — | EP | claimed |
| WO-2012143143-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2012-10-26 | — | — | WO | claimed |
| CN-101175493-A | Method for treating actinic keratosis | 3M INNOVATIVE PROPERTIES CO (US) | 2008-05-07 | — | — | CN | claimed |
| CN-101155813-A | Ethanesulfonic acid salt of 1- (2-methylpropyl) -1H-imidazo [4, 5-C ] [1,5] naphthyridin-4-amine and methanesulfonic acid salt of 1- (2-methylpropyl) -1H-imidazo [4, 5-C ] [1,5] naphthyridin-4-amine | TAKEDA PHARMACEUTICAL (JP) | 2008-04-02 | — | — | CN | claimed |
| CN-101146807-A | Process for the preparation of 2-methyl-1- (2-methylpropyl) -1H-imidazo [4, 5-C ] [1,5] naphthyridin-4-amine | 3M INNOVATIVE PROPERTIES CO (US) | 2008-03-19 | — | — | CN | claimed |
| CN-1845736-A | Methods related to the treatment of mucosal associated conditions | 3M INNOVATIVE PROPERTIES CO (US) | 2006-10-11 | — | — | CN | claimed |
| EP-1450804-A1 | PHARMACEUTICAL FORMULATIONS COMPRISING AN IMMUNE RESPONSE MODIFIER | 3M Innovative Properties Company (US) | 2004-09-01 | — | — | EP | claimed |
| CN-1147493-C | Oxazolo, thiazolo and selenazolo [4,5-C]-quinolin-4-amines and analoges thereof | 3M | 2004-04-28 | — | — | CN | claimed |
| WO-2003045391-A1 | PHARMACEUTICAL FORMULATIONS COMPRISING AN IMMUNE RESPONSE MODIFIER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-06-05 | — | — | WO | claimed |
| EP-1075478-B1 | PHENYLUREA AND PHENYLTHIO UREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | claimed |
| CN-1320126-A | Oxazolo, thiazolo and selenazolo [4, 5-C ] quinolin-4-amines and analogs thereof | 3M INNOVATIVE PROPERTIES CO (US) | 2001-10-31 | — | — | CN | claimed |
| WO-2025039979-A1 | PROTEIN ARGININE METHYLTRANSFERASE-5 INHIBITOR AND PHARMACEUTICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2025-02-27 | — | — | WO | disclosed |
| US-20240343710-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. | 2024-10-17 | — | — | US | disclosed |
| CN-113166143-B | N-1 branched alkyl ether substituted imidazo [4,5-c ] quinoline compounds, compositions and methods | 舒万诺知识产权公司 | 2024-06-04 | — | — | CN | disclosed |
| US-4347362-A | HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |
| US-4324893-A | 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-04-13 | — | — | US | disclosed |
| EP-0018735-A1 | 1,8-Naphthyridine derivatives, their preparation, pharmaceutical compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-11-12 | — | — | EP | disclosed |
| WO-1980002287-A1 | 1,8-NAPHTHYRIDINE DERIVATIVES | AMERICAN HOME PROD (US) | 1980-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343710-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | PARP1, PARP11, PARP12 | NCF1 1065/4885MAPT 4689/4885HSP90AA1 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.