SCHEMBL19600404

SCHEMBL19600404

c1ccc(-c2cccc3ccc(-c4ccc5c6c(cccc46)Oc4cc(-c6c7ccccc7cc7ccccc67)ccc4-5)cc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
MAPK1 P28482 2/20 0.40
ATM Q13315 1/20 0.40
ALOX5 P09917 2/20 0.35
GPR84 Q9NQS5 6/20 0.35
ANPEP P15144 1/20 0.35
CES1 P23141 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MCL1 Q07820 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
NQO2 P16083 1/20 0.32
TNF P01375 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16376406 0.90 KDM4E (0.40) KDM4EMAPK1ATMALOX5GPR84
SCHEMBL19600399 0.88 GPR84 (0.41) KDM4EMAPK1ATMALOX5GPR84
SCHEMBL19600405 0.88 KDM4E (0.49) KDM4EMAPK1ATMMEN1KMT2A
SCHEMBL25166654 0.87 KDM4E (0.48) KDM4EMAPK1ATMANPEPMEN1
SCHEMBL16376372 0.87 KDM4E (0.43) KDM4EMAPK1ATMGPR84MEN1
SCHEMBL16376392 0.87 KDM4E (0.47) KDM4EMAPK1ATMMEN1KMT2A
SCHEMBL25166630 0.86 KDM4E (0.43) KDM4EMAPK1ATMANPEPMEN1
SCHEMBL19600430 0.84 KDM4E (0.45) KDM4EMAPK1ATMGPR84MEN1
SCHEMBL19600402 0.84 KDM4E (0.47) KDM4EMAPK1ATMGPR84MEN1
SCHEMBL19600420 0.83 KDM4E (0.44) KDM4EMAPK1ATMGPR84MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573825-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573825-B2 Compound and organic light-emitting device including the same CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.