SCHEMBL17265405

SCHEMBL17265405

c1ccc(-c2cc(-c3ccc4c(c3)Oc3cccc5c3c-4cc3c4ccccc4c(-c4ccc6c(c4)oc4ccccc46)cc53)c3ccccc3c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
HCRTR1 O43613 1/20 0.32
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
AHR P35869 1/20 0.30
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30
ALOX5 P09917 1/20 0.30
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600408 0.92 KDM4E (0.35) HSD17B1HSD17B2HCRTR1MMP12MMP13
SCHEMBL17265416 0.86 KDM4E (0.34) KDM4EMAPK1ATMAHR
SCHEMBL17265407 0.83 PLA2G2A (0.38) KDM4EMAPK1ATMAHRPLA2G2A
SCHEMBL17886386 0.83 MMP12 (0.31) HSD17B1HSD17B2MMP12MMP13PLA2G2A
SCHEMBL17265392 0.82 KDM4E (0.37) HSD17B1HSD17B2KDM4EMAPK1ATM
SCHEMBL17265389 0.81 ALDH1A1 (0.42) HSD17B1HSD17B2KDM4EMAPK1ATM
SCHEMBL17265386 0.81 CA12 (0.38) KDM4EMAPK1ATMAHRGPR84
SCHEMBL17265401 0.81 ALOX5 (0.46) ATMPLA2G2APLA2G4AALOX5
SCHEMBL20305991 0.80 PLA2G2A (0.39) KDM4EMAPK1ATMAHRPLA2G2A
SCHEMBL13507526 0.80 MAPK1 (0.35) KDM4EMAPK1ATMAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed