SCHEMBL19600408

SCHEMBL19600408

c1ccc(-c2cc(-c3ccc4c(c3)Oc3cccc5c(-c6ccc7c(c6)oc6ccccc67)ccc-4c35)c3ccccc3c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
HCRTR1 O43613 1/20 0.33
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
AHR P35869 1/20 0.32
PLA2G2A P14555 2/20 0.31
PLA2G4A P47712 2/20 0.31
ALOX5 P09917 1/20 0.31
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
KMT2A Q03164 2/20 0.31
MPI P34949 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
DUSP3 P51452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17265405 0.92 HSD17B1 (0.33) KDM4EMAPK1ATMHSD17B1HSD17B2
SCHEMBL19600429 0.86 KDM4E (0.47) KDM4EMAPK1ATMHSD17B1HSD17B2
SCHEMBL19600437 0.82 PLA2G2A (0.41) KDM4EMAPK1ATMMMP12MMP13
SCHEMBL19600414 0.81 PLA2G2A (0.40) KDM4EMAPK1ATMAHRPLA2G2A
SCHEMBL17886386 0.81 MMP12 (0.31) HSD17B1HSD17B2MMP12MMP13PLA2G2A
SCHEMBL26164391 0.80 HCRTR1 (0.33) KDM4EMAPK1ATMHSD17B1HSD17B2
SCHEMBL19600420 0.80 KDM4E (0.44) KDM4EMAPK1ATMHSD17B1HSD17B2
SCHEMBL19600407 0.80 KDM4E (0.43) KDM4EMAPK1ATMHSD17B1HSD17B2
SCHEMBL19600405 0.79 KDM4E (0.49) KDM4EMAPK1ATMMEN1ALDH1A1
SCHEMBL26164381 0.79 MMP12 (0.34) KDM4EMAPK1ATMHCRTR1MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573825-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573825-B2 Compound and organic light-emitting device including the same CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.