Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17268485 | 0.88 | LTA4H (0.42) | ALDH1A1IDO1SLC1A1SMN1; SMN2LTA4H | |
| SCHEMBL25252674 | 0.86 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2AMAPK1L3MBTL1 | |
| SCHEMBL19458945 | 0.86 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2AMAPK1L3MBTL1 | |
| SCHEMBL13561435 | 0.85 | LTA4H (0.41) | ALDH1A1IDO1SLC1A1SMN1; SMN2LTA4H | |
| SCHEMBL3247652 | 0.85 | KIF11 (0.41) | IDO1SMN1; SMN2LTA4HKMT2A | |
| Hydrochloric Acid SCHEMBL25359940 | 0.85 | KIF11 (0.41) | IDO1SMN1; SMN2LTA4HKMT2A | |
| SCHEMBL3247655 | 0.85 | KIF11 (0.41) | IDO1SMN1; SMN2LTA4HKMT2A | |
| Hydrochloric Acid SCHEMBL25359945 | 0.85 | KIF11 (0.41) | IDO1SMN1; SMN2LTA4HKMT2A | |
| SCHEMBL19520974 | 0.85 | KIF11 (0.41) | IDO1SMN1; SMN2LTA4HKMT2A | |
| SCHEMBL3148201 | 0.84 | ALDH1A1 (0.44) | ALDH1A1IDO1SLC1A1SMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328109-A1 | DERMAL COMPOSITIONS CONTAINING UNNATURAL HYGROSCOPIC AMINO ACIDS | MEDPHARM LIMITED (GB) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150328109-A1 | DERMAL COMPOSITIONS CONTAINING UNNATURAL HYGROSCOPIC AMINO ACIDS | AADAT, HACL2, SLC6A15 | ALDH1A1 1604/4885IDO1 159/4885SLC1A1 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.