Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17268486 | 0.84 | ALDH1A1 (0.42) | ALDH1A1IDO1SLC1A1SMN1; SMN2LTA4H | |
| SCHEMBL5831739 | 0.83 | SLC15A1 (0.47) | ALDH1A1BTN3A1ATMSLC15A1CA12 | |
| SCHEMBL7417051 | 0.83 | BTN3A1 (0.43) | ALDH1A1BTN3A1ATMLTA4HSLC15A1 | |
| SCHEMBL27396151 | 0.81 | LTA4H (0.43) | ALDH1A1BTN3A1IDO1SLC1A1SMN1; SMN2 | |
| SCHEMBL2367427 | 0.80 | ALDH1A1 (0.49) | ALDH1A1IDO1SLC1A1SMN1; SMN2LTA4H | |
| SCHEMBL8012615 | 0.80 | ALDH1A1 (0.49) | ALDH1A1IDO1SLC1A1SMN1; SMN2LTA4H | |
| Hydrochloric Acid SCHEMBL29401415 | 0.79 | ALDH1A1 (0.47) | ALDH1A1IDO1SLC1A1SMN1; SMN2LTA4H | |
| Hydrochloric Acid SCHEMBL29399154 | 0.79 | ALDH1A1 (0.47) | ALDH1A1IDO1SLC1A1SMN1; SMN2LTA4H | |
| SCHEMBL13535118 | 0.79 | LTA4H (0.49) | ALDH1A1BTN3A1LTA4HSLC15A1LAP3 | |
| Hydrochloric Acid SCHEMBL25224887 | 0.78 | ALDH1A1 (0.53) | ALDH1A1IDO1SLC1A1SMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100135960-A1 | ANTIVIRAL ACYLSULFONAMIDE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2010-06-03 | — | — | US | disclosed |
| US-20100074863-A1 | ANTI-INFECTIVE PYRROLIDINE DERIVATIVES AND ANALOGS | ENANTA PHARMACEUTICALS, INC. | 2010-03-25 | — | — | US | disclosed |
| US-20090326019-A1 | 3,4-BICYCLIC PYRROLIDINE ANTIVIRALS | ENANTA PHARMACEUTICALS, INC. | 2009-12-31 | — | — | US | disclosed |
| US-20090233972-A1 | SUBSTITUTED HETEROCYCLES AS ANTI-INFECTIVES | ENANTA PHARMACEUTICALS, INC. | 2009-09-17 | — | — | US | disclosed |
| US-20090060874-A1 | BICYCLIC PYRROLIDINE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2009-03-05 | — | — | US | disclosed |
| US-20090053175-A1 | SUBSTITUTE PYRROLIDINE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2009-02-26 | — | — | US | disclosed |
| US-20090047247-A1 | Pyrrolidine Derivatives | ENANTA PHARMACEUTICALS, INC. | 2009-02-19 | — | — | US | disclosed |
| US-20090022689-A1 | C4-SPIRO-PYRROLIDINE ANTIVIRALS | ENANTA PHARMACEUTICALS, INC. | 2009-01-22 | — | — | US | disclosed |
| US-20090004140-A1 | 4-SUBSTITUTED PYRROLIDINE AS ANTI-INFECTIVES | ENANTA PHARMACEUTICALS, INC. | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326019-A1 | 3,4-BICYCLIC PYRROLIDINE ANTIVIRALS | ZC3HAV1, EIF2AK2, POLRMT | ALDH1A1 494/4885BTN3A1 3190/4885IDO1 270/4885 |
| US-20090004140-A1 | 4-SUBSTITUTED PYRROLIDINE AS ANTI-INFECTIVES | EIF2AK2, RNGTT, POLR2E | ALDH1A1 539/4885BTN3A1 4336/4885IDO1 500/4885 |
| US-20090022689-A1 | C4-SPIRO-PYRROLIDINE ANTIVIRALS | ZC3HAV1, HAVCR2, HCCS | ALDH1A1 274/4885BTN3A1 3984/4885IDO1 1340/4885 |
| US-20090053175-A1 | SUBSTITUTE PYRROLIDINE DERIVATIVES | POLRMT, EIF2AK2, NSUN2 | ALDH1A1 442/4885BTN3A1 4264/4885IDO1 495/4885 |
| US-20100074863-A1 | ANTI-INFECTIVE PYRROLIDINE DERIVATIVES AND ANALOGS | ZC3HAV1, POLRMT, EIF2AK2 | ALDH1A1 1025/4885BTN3A1 4214/4885IDO1 654/4885 |
| US-20090060874-A1 | BICYCLIC PYRROLIDINE DERIVATIVES | EIF2AK2, ZC3HAV1, POLRMT | ALDH1A1 616/4885BTN3A1 3255/4885IDO1 518/4885 |
| US-20090233972-A1 | SUBSTITUTED HETEROCYCLES AS ANTI-INFECTIVES | HAVCR2, EIF2AK2, HCCS | ALDH1A1 424/4885BTN3A1 4020/4885IDO1 976/4885 |
| US-20100135960-A1 | ANTIVIRAL ACYLSULFONAMIDE DERIVATIVES | EIF2AK2, NSUN3, ACSS2 | ALDH1A1 734/4885BTN3A1 4350/4885IDO1 995/4885 |
| US-20090047247-A1 | Pyrrolidine Derivatives | ZC3HAV1, EIF2AK2, POLRMT | ALDH1A1 528/4885BTN3A1 4141/4885IDO1 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.