SCHEMBL1727516

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1727519	0.88	SMN1; SMN2 (0.59)	SMN1; SMN2PKMNPC1ALDH1A1HTT
	SCHEMBL4431424	0.78	SMN1; SMN2 (0.65)	SMN1; SMN2PKMNPC1ALDH1A1HTT
	SCHEMBL3574415	0.77	CYP2C9 (0.60)	SMN1; SMN2NPC1ALDH1A1TDP1KDM4E
	SCHEMBL5216548	0.76	SMN1; SMN2 (0.63)	SMN1; SMN2PKMALDH1A1HTTNPSR1
	SCHEMBL1839628	0.76	SMN1; SMN2 (0.76)	SMN1; SMN2PKMNPC1ALDH1A1HTT
	SCHEMBL1728847	0.76	CYP2C9 (0.59)	SMN1; SMN2ALDH1A1HTTLMNAKMT2A
	SCHEMBL1728366	0.76	SMN1; SMN2 (0.62)	SMN1; SMN2NPC1ALDH1A1HTTNPSR1
	SCHEMBL7238822	0.76	ALDH1A1 (0.64)	SMN1; SMN2PKMALDH1A1HTTLMNA
	SCHEMBL1727617	0.76	HSD11B1 (0.59)	SMN1; SMN2ALDH1A1HTTTDP1KMT2A
	SCHEMBL27080814	0.75	SMN1; SMN2 (0.73)	SMN1; SMN2PKMNPC1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.