Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727952 | 0.81 | NOTUM (0.47) | LMNAHTTMAPTHPGDPOLB | |
| SCHEMBL1729368 | 0.76 | NOTUM (0.49) | LMNAHTTMAPTHPGDPOLB | |
| SCHEMBL1729344 | 0.74 | KDM4E (0.44) | LMNAHTTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL1727690 | 0.72 | POLB (0.44) | LMNAHTTMAPTHPGDPOLB | |
| SCHEMBL1733940 | 0.68 | SIGMAR1 (0.60) | LMNAMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL1727951 | 0.66 | NOTUM (0.49) | LMNAHTTMAPTPOLBALDH1A1 | |
| SCHEMBL1727891 | 0.65 | ALDH1A1 (0.43) | HTTMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL5232337 | 0.65 | LMNA (0.45) | LMNAHTTMAPTHPGDPOLB | |
| SCHEMBL6256297 | 0.64 | LMNA (0.71) | LMNAHTTMAPTPOLBALDH1A1 | |
| SCHEMBL1728028 | 0.64 | NOTUM (0.47) | LMNAHTTMAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |