Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729368 | 0.86 | NOTUM (0.49) | NOTUMPOLBLMNAMAPK1RAB9A | |
| SCHEMBL1727692 | 0.81 | LMNA (0.42) | NOTUMPOLBLMNAMAPK1RAB9A | |
| SCHEMBL1730128 | 0.76 | HTR3A (0.43) | POLBLMNARAB9ATRPV1SMN1; SMN2 | |
| SCHEMBL1728682 | 0.76 | ACACB (0.40) | ACACB | |
| SCHEMBL1728140 | 0.75 | ABL1 (0.35) | TRPV1 | |
| SCHEMBL1727875 | 0.75 | ACACB (0.40) | ACACB | |
| SCHEMBL1729264 | 0.74 | HTR3A (0.41) | — | |
| SCHEMBL1727768 | 0.73 | HRH3 (0.37) | ACACB | |
| SCHEMBL1730195 | 0.73 | HCAR2 (0.46) | RAB9AHTTMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1728165 | 0.73 | KDM4E (0.45) | LMNARAB9AHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |