Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 3/20 | 0.35 |
| ▸ | SKP1 | P63208 | 3/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728810 | 0.88 | CKS1B (0.38) | HRH3MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL1727727 | 0.86 | MAP4K4 (0.40) | MAP4K4FFAR4CKS1BSKP1SKP2 | |
| SCHEMBL1728683 | 0.85 | DRD3 (0.40) | MAP4K4CKS1BSKP1SKP2ACACB | |
| SCHEMBL1727877 | 0.84 | ACACB (0.39) | MAP4K4FFAR4CKS1BSKP1SKP2 | |
| SCHEMBL1727578 | 0.81 | ENPP2 (0.42) | HRH3MAP4K4MCHR1AOC3RORC | |
| SCHEMBL1728164 | 0.81 | KDM4E (0.45) | HRH3MAP4K4ACACB | |
| SCHEMBL1727922 | 0.81 | DRD2 (0.46) | DRD2DRD3HTR1A | |
| SCHEMBL1729590 | 0.79 | PTGES (0.46) | MAP4K4CKS1BSKP1SKP2DRD2 | |
| SCHEMBL1727890 | 0.79 | HTR1A (0.40) | MAP4K4ACACBHTR1A | |
| SCHEMBL1727647 | 0.79 | MAP4K4 (0.40) | MAP4K4FFAR4CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |