Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 6/20 | 0.51 |
| ▸ | NSD2 | O96028 | 4/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728655 | 0.88 | MALT1 (0.45) | CHRM4MALT1KMT2A | |
| SCHEMBL1730153 | 0.84 | CHRM4 (0.52) | CHRM4NSD2SIRT2SIRT1SIRT3 | |
| SCHEMBL3266163 | 0.83 | SIRT2 (0.44) | CHRM4NSD2SIRT2SIRT1SIRT3 | |
| SCHEMBL1727887 | 0.83 | KDM4E (0.60) | CHRM4MALT1 | |
| SCHEMBL1728967 | 0.80 | NSD2 (0.47) | CHRM4NSD2 | |
| SCHEMBL1728813 | 0.80 | SIRT2 (0.51) | CHRM4SIRT2SIRT1SIRT3MALT1 | |
| SCHEMBL1727741 | 0.79 | CHRM4 (0.56) | CHRM4 | |
| SCHEMBL1728915 | 0.79 | KMT2A (0.50) | MALT1KMT2A | |
| SCHEMBL1727503 | 0.77 | DRD2 (0.56) | SIRT2SIRT1SIRT3 | |
| SCHEMBL4879872 | 0.77 | KDM4E (0.60) | MALT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |