SCHEMBL172793

SCHEMBL172793

CC(=O)c1cccc(I)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
MTOR P42345 3/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
GRM5 P41594 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
TP53BP1 Q12888 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
HTT P42858 1/20 0.43
CREBBP Q92793 1/20 0.43
MAOB P27338 1/20 0.43
MAPK1 P28482 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27775594 0.86 MTOR (0.46) ALDH1A1MTORMEN1KMT2AHDAC1
SCHEMBL279656 0.83 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ASMN1; SMN2TDP1
SCHEMBL18079795 0.81 CES2 (0.54) MTORHDAC1HDAC2GRM5TP53BP1
SCHEMBL18242327 0.81 MTOR (0.44) MTORHDAC1HDAC2GRM5TP53BP1
SCHEMBL3673834 0.81 ATM (0.58) ALDH1A1MTORHDAC1HDAC2GRM5
Ethane SCHEMBL7579504 0.80 MTOR (0.55) ALDH1A1MTORMEN1KMT2AHDAC1
SCHEMBL40282 0.79 CA12 (0.58) ALDH1A1MTORMEN1KMT2ATDP1
SCHEMBL29532021 0.79 CA12 (0.58) ALDH1A1MTORMEN1KMT2ATDP1
SCHEMBL2163420 0.79 HDAC1 (0.45) MTORHDAC1HDAC2GRM5TDP1
SCHEMBL7923301 0.78 HDAC1 (0.49) MTORMEN1KMT2AHDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581071-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-07-09 EP claimed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO claimed
CN-106010316-A Adhesive for steel volute and preparation method thereof 保定亿嘉特种陶瓷制造有限公司 2016-10-12 CN claimed
US-12617789-B2 Small molecular inhibitors of NF-κb inducing kinase JANSSEN PHARMACEUTICA NV (BE) 2026-05-05 US disclosed
EP-4667458-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER, COMPRISING SOS1 INHIBITOR AND ANTICANCER DRUG Kanaph Therapeutics Inc. (KR) 2025-12-24 EP disclosed
EP-4648762-A2 PPARG MODULATORS University of Florida Research Foundation, Incorporated (US) 2025-11-19 EP disclosed
US-20250270220-A1 SOS1 INHIBITORS Mirati Therapeutics, Inc. (US) 2025-08-28 US disclosed
US-20250215030-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
US-12331240-B2 Anthraquinone compound, liquid crystal composition containing said compound, and light-controlling element NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-06-17 US disclosed
US-20250179103-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS RECLUDIX PHARMA, INC. 2025-06-05 US disclosed
US-12304915-B2 SOS1 inhibitors Mirati Therapeutics, Inc. (US) 2025-05-20 US disclosed
WO-2000009115-A1 GRP RECEPTOR LIGANDS SMITHKLINE BEECHAM CORPORATION (US) 2000-02-24 WO disclosed
WO-2000009116-A1 GRP RECEPTOR LIGANDS SMITHKLINE BEECHAM CORPORATION (US) 2000-02-24 WO disclosed
WO-1999062520-A1 HIV INTEGRASE INHIBITORS MERCK & CO., INC. (US) 1999-12-09 WO disclosed
WO-1999059971-A1 NOVEL 4-PHENYLPIPERIDINES FOR THE TREATMENT OF PRURITIC DERMATOSES PFIZER INC. (US) 1999-11-25 WO disclosed
US-5939545-A MODULATING THE GABA.SUB.A (GAMMA-AMINOBUTYRIC ACID A) RECEPTOR-CHLORIDE IONOPHORE COMPLEX TO ALLEVIATE STRESS, ANXIETY, SEIZURES, MOOD DISORDERS, PMS (PREMENSTRUAL SYNDROME) AND PND (POSTNATAL DEPRESSION) AND TO INDUCE ANESTHESIA COCENSYS, INC. (US) 1999-08-17 US disclosed
WO-1998045265-A1 PROCESS FOR COVALENTLY COUPLING ORGANIC COMPOUNDS UTILIZING DIBORON DERIVATIVES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1998-10-15 WO disclosed
EP-0752860-A4 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS INC (US) 1998-05-06 EP disclosed
EP-0752860-A1 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS, INC. (US) 1997-01-15 EP disclosed
WO-1995021617-A1 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS, INC. (US) 1995-08-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179103-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS STAT6, STAT3, STAT1 ALDH1A1 531/4885MTOR 262/4885MEN1 1979/4885
US-20250215030-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A ALDH1A1 3030/4885MTOR 171/4885MEN1 2739/4885
US-12304915-B2 SOS1 inhibitors SOS1, SOS2, SAV1 ALDH1A1 3260/4885MTOR 1373/4885MEN1 214/4885
US-20250270220-A1 SOS1 INHIBITORS SOS1, SOS2, SAV1 ALDH1A1 3260/4885MTOR 1373/4885MEN1 214/4885
US-12617789-B2 Small molecular inhibitors of NF-κb inducing kinase IRAK3, IKBKB, IKBKG ALDH1A1 3824/4885MTOR 488/4885MEN1 3685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.