SCHEMBL17280209

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20382903	0.90	LMNA (0.40)	LMNAGAAMAPTTDP1BACE1
	SCHEMBL17280199	0.77	ADORA3 (0.43)	LMNAGAAMAPTTDP1BACE1
	SCHEMBL17279946	0.77	MAPT (0.47)	LMNAGAAMAPTBACE1CYP3A4
	SCHEMBL27935472	0.75	BACE1 (0.70)	LMNAGAAMAPTTDP1BACE1
	SCHEMBL28032593	0.73	LMNA (0.66)	LMNAGAAMAPTTDP1BACE1
	SCHEMBL17280176	0.73	CYP1A1 (0.53)	LMNAGAACYP3A4ALDH1A1KDM4E
	Acetic Acid Phenyl Ester SCHEMBL27925284	0.72	MAPT (0.69)	LMNAGAAMAPTTDP1BACE1
	SCHEMBL13737920	0.72	LMNA (0.50)	LMNAGAAMAPTTDP1ACHE
	SCHEMBL17280205	0.71	MAPT (0.55)	LMNAGAAMAPTKMT2ASMN1; SMN2
	SCHEMBL4446422	0.71	MAPT (0.67)	LMNAGAAMAPTTDP1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.