Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728014 | 0.86 | NPC1 (0.45) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL1727755 | 0.82 | NAMPT (0.53) | RAB9ALMNAPKMMEN1KMT2A | |
| SCHEMBL1727677 | 0.82 | NAMPT (0.55) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL1727700 | 0.78 | KMT2A (0.50) | RAB9ANPC1LMNAPKMMEN1 | |
| SCHEMBL1726833 | 0.78 | KDM4A (0.60) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL1728219 | 0.78 | NAMPT (0.49) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL1727761 | 0.78 | KMT2A (0.41) | LMNAMEN1KMT2A | |
| SCHEMBL1726674 | 0.77 | NPC1 (0.52) | RAB9ANPC1LMNAATMPKM | |
| SCHEMBL1727814 | 0.77 | AKR1C3 (0.46) | MEN1KMT2A | |
| SCHEMBL1727751 | 0.76 | PARP1 (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403499-A2 | METHODS AND COMPOSITIONS USEFUL IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | Stemsynergy Therapeutics, Inc (US) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010101964-A2 | METHODS AND COMPOSITIONS USEFUL IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS, INC (US) | 2010-09-10 | — | — | WO | disclosed |