Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.42 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727927 | 0.82 | HRH4 (0.44) | DRD2ACACBPHGDH | |
| SCHEMBL1730154 | 0.81 | DRD2 (0.42) | HTR1ADRD2HTR2AACACBACACA | |
| SCHEMBL1729260 | 0.80 | HTR3A (0.42) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL1728164 | 0.80 | KDM4E (0.45) | ACACBACACA | |
| SCHEMBL1730124 | 0.79 | CHRM4 (0.46) | DRD2HTR2AHTR7HTR6CKS1B | |
| SCHEMBL1730192 | 0.78 | CKS1B (0.46) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL1727922 | 0.77 | DRD2 (0.46) | HTR1ADRD2HTR2A | |
| SCHEMBL1727727 | 0.77 | MAP4K4 (0.40) | DRD2ACACBCKS1BSKP1SKP2 | |
| SCHEMBL237971 | 0.77 | CYP11B2 (0.44) | CYP11B2CYP11B1CDK8HTR1ADRD2 | |
| SCHEMBL1728859 | 0.77 | CYP11B2 (0.48) | CYP11B2CYP11B1CDK8HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |