Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727960 | 0.90 | DRD4 (0.56) | DRD4CNR1ALDH1A1HTR1AHTR2A | |
| SCHEMBL1727631 | 0.87 | HTR1A (0.48) | DRD4HTR1AHTR2ADRD3HTR2C | |
| SCHEMBL1727728 | 0.86 | CNR1 (0.47) | DRD4CNR1POLBHTR1AHTR2A | |
| SCHEMBL14796938 | 0.84 | CHRM4 (0.49) | CNR1LMNAACHE | |
| SCHEMBL1728645 | 0.83 | CNR1 (0.50) | DRD4CNR1HTR1AHTR2ADRD3 | |
| SCHEMBL1729537 | 0.81 | DRD4 (0.55) | DRD4POLBLMNAFAAHACHE | |
| SCHEMBL1727657 | 0.80 | CNR1 (0.54) | CNR1ALDH1A1POLBHTR1AHTR2A | |
| SCHEMBL1727394 | 0.79 | HTR1A (0.46) | DRD4CNR1HTR1AHTR2ADRD3 | |
| SCHEMBL1730370 | 0.79 | CNR1 (0.44) | DRD4CNR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL1729806 | 0.79 | CNR1 (0.44) | DRD4CNR1ALDH1A1HSD17B10HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |