Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 4/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727394 | 0.90 | HTR1A (0.46) | HTR1ACHRM4HTR2ADRD3DRD2 | |
| SCHEMBL1728049 | 0.87 | DRD4 (0.51) | HTR1AHTR2ADRD3DRD2DRD4 | |
| SCHEMBL1727728 | 0.83 | CNR1 (0.47) | HTR1AHTR2ADRD3DRD2DRD4 | |
| SCHEMBL1727526 | 0.82 | HRH2 (0.47) | HTR1ACHRM4HTR2ADRD3DRD4 | |
| SCHEMBL1728645 | 0.81 | CNR1 (0.50) | HTR1AHTR2ADRD3DRD2DRD4 | |
| SCHEMBL1728079 | 0.81 | DRD2 (0.42) | HTR1ASUCNR1HTR2ADRD3SCN10A | |
| SCHEMBL1729330 | 0.80 | MCHR1 (0.41) | HTR1ASUCNR1HTR2ADRD3SCN10A | |
| SCHEMBL1727960 | 0.79 | DRD4 (0.56) | HTR1AHTR2ADRD3DRD2DRD4 | |
| SCHEMBL1728735 | 0.78 | DRD4 (0.49) | HTR1ACHRM4HTR2ADRD3DRD4 | |
| SCHEMBL1727657 | 0.78 | CNR1 (0.54) | HTR1AHTR2ADRD3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |