Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729632 | 0.90 | CNR1 (0.51) | CNR1HTR1AHTR2ADRD3HTR2C | |
| SCHEMBL1727728 | 0.86 | CNR1 (0.47) | CNR1HTR1AHTR2ADRD3HTR2C | |
| SCHEMBL1728049 | 0.83 | DRD4 (0.51) | CNR1HTR1AHTR2ADRD3HTR2C | |
| SCHEMBL1727732 | 0.81 | CD274 (0.50) | CD274HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL1727631 | 0.81 | HTR1A (0.48) | HTR1AHTR2ADRD3HTR2CHTR7 | |
| SCHEMBL1727657 | 0.80 | CNR1 (0.54) | CNR1HTR1AHTR2ADRD3HTR2C | |
| SCHEMBL1728853 | 0.79 | CNR1 (0.44) | CNR1HTR1AHTR2ADRD3HTR2C | |
| SCHEMBL1727866 | 0.78 | CNR1 (0.44) | CNR1HTR1AHTR2ADRD3HTR2C | |
| SCHEMBL1727960 | 0.78 | DRD4 (0.56) | CNR1HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL1727411 | 0.77 | DRD4 (0.47) | HTR1AHTR2ADRD3DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |